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Novartis to Buy Excellergy for up to $2 Billion
Novartis is acquiring Excellergy's next-generation anti-IgE drug Exl-111 to strengthen its allergy portfolio amid patent expirations and revenue pressures.
- On Friday, March 27, 2026, Palo Alto-based biotechnology firm Excellergy announced it will be acquired by Novartis in a transaction valued at up to $2 billion in upfront and milestone payments.
- The deal centers on Excellergy's novel trifunctional Effector Cell Response Inhibitors , with lead candidate Exl-111 designed to disarm allergic effector cells by targeting the IgE axis.
- Exl-111 is currently in Phase 1 development and has the potential to deliver faster, deeper suppression of IgE signaling and improved symptom control compared to conventional anti-IgE therapies.
- "This acquisition validates the transformative potential of our ECRIs," said Todd Zavodnick, Chief Executive Officer of Excellergy, noting Novartis brings global capabilities to realize the medicine's full potential.
- Fiona Marshall, President of Biomedical Research at Novartis, noted the program builds on biology the company knows well, while J.P. Morgan Securities LLC served as exclusive financial advisor.
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Excellergy specializes in the development of therapies for the possible treatment of allergic diseases such as food allergies, chronic hives or asthma.
·Düsseldorf, Germany
Read Full ArticleNovartis agrees to acquire Excellergy, Inc., building on allergy leadership with next-generation anti-IgE innovation
Proposed acquisition strengthens Novartis immunology strategy in food allergy and other IgE-driven diseases - Lead asset Exl-111 builds on proven IgE biology with a...
·Manila, Philippines (the)
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