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4D Brain Map Uncovers Early Signs of Multiple Sclerosis

Summary by European Medical Journal

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Multiple Sclerosis Research Blog

B cell cytokines the marker to success in early MS

Tweet CXCL13 is a cytokines that attracts B cells in this study they claim that if one has a low level of CXCL 13 in the CNS then lower efficacy DMT work at the first presentation of MS but a high level predicts failure. I am not a neuro but one could ask why start with lower efficacy agents start with high efficacy agents and avoid risk of failure. highlights • In patients with clinically isolated syndrome(CIS), the CXCL13 index predicted resp…

4 days ago

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Stemwell Science News

Epstein-Barr Virus Infection Promotes T Cell Dysregulation in a Humanized Mouse Model of Multiple Sclerosis

Donor Epstein-Barr virus (EBV) seropositivity and relapsing multiple sclerosis diagnosis were associated with a significant increase in the number of central nervous system (CNS) infiltrating effector T cells due to enhanced proliferation of proinflammatory T cells and limited expansion of regulatory T cells. [Science Advances] Full Article

4 days ago

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