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Engineered mini CRISPR enzyme gets a 60-fold power boost for gene editing
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Engineered mini CRISPR enzyme gets a 60-fold power boost for gene editing
A tiny molecular scissor that once barely worked in human cells has been transformed into a high-performance genome-editing platform, thanks to a clever engineering strategy that swapped a handful of amino acids and trimmed the enzyme’s RNA guide. In a study published in Molecular Systems Biology, researchers report that a compact CRISPR nuclease called CgCas12n, […]
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