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Engineered Bacterium Turns Ethanol Into Cinnamic Acid in First-of-its-Kind
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Engineered Bacterium Turns Ethanol Into Cinnamic Acid in First-of-its-Kind
Researchers at RIKEN have engineered the methylotrophic bacterium Methylorubrum extorquens PA1 to produce cinnamic acid directly from ethanol by repairing an acetyl-CoA bottleneck and boosting the shikimate pathway, achieving 52.34 milligrams per liter in fed-batch culture.
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