Endothelial Insulin Resistance Induced by Adrenomedullin Mediates Obesity-Associated Diabetes
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Endothelial Insulin Resistance Induced by Adrenomedullin Mediates Obesity-Associated Diabetes
The authors discovered that adrenomedullin, a peptide hormone that increased in concentration in the setting of obesity, inhibited insulin signaling in the endothelium of both humans and mice. [Science] Abstract
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