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CVS drops Zepbound from preferred coverage in major blow to Eli Lilly

  • On May 1, 2025, CVS Health announced it will drop Eli Lilly's weight-loss drug Zepbound from its standard formulary starting July 1 in the U.S.
  • CVS prioritized Novo Nordisk's Wegovy and Saxenda as preferred drugs due to negotiated discounts and easing drug shortages affecting coverage decisions.
  • Zepbound and Wegovy, both GLP-1 receptor agonists used for obesity treatment, have seen soaring popularity despite patchy coverage driven by cost and supply issues.
  • Zepbound's first-quarter sales rose from $517 million to $2.3 billion year-over-year, but Lilly’s shares fell nearly 11%, closing at $804.06 Thursday afternoon.
  • The formulary change may complicate patient access to Zepbound and could force Lilly to reduce prices to regain coverage amid strong competition from Novo.
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Lilly star weight-loss drug Zepbound faces coverage challenge from CVS Health

Eli Lilly’s stock wobbled Thursday after a looming coverage hit was detailed for its blockbuster weight-loss drug Zepbound.

·United States
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New Hampshire Union Leader broke the news in New Hampshire, United States on Thursday, May 1, 2025.
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