Electronic Implant Lowers Blood Glucose and Reduces Weight in Mice
The wireless implant oxidizes glucose into gluconate and ran autonomously for two weeks in closed-loop tests, researchers said.
- ETH Zurich bioengineer Martin Fussenegger developed a wireless implant named ECHO that regulates blood glucose in diabetic mice by converting excess sugar into gluconate without medication.
- Inside the device, a graphite wafer studded with gold nanoclusters and platinum particles acts as a catalyst, powered wirelessly at 13.56 MHz through a smartphone-connected glucose sensor.
- In experiments, diabetic mice with the implant showed precisely regulated blood sugar, reduced triglycerides, and weight loss, operating reliably for six weeks with no evidence of tissue damage, according to the study published in Science.
- While researchers have not yet tested the device on humans, they plan to develop it into a clinical medical device, noting that the cell-free design could simplify technical development.
- Traditional treatments like insulin injections are prone to side effects and struggle to match the body's natural glucose management, leading Fussenegger to hope this system might eventually allow patients to "forget my diabetes.
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A team of Swiss researchers has tested an implant as a method to control glucose and weight.
Diabetes and obesity: electronic device controls glucose and reduces weight in animal tests Adobe Stock A small electronic device implanted under the skin managed to normalize blood sugar levels and reduce by up to 10% the body weight of mice with type 2 diabetes and obesity, without the administration of medications. The technology uses electricity to transform part of circulating glucose into a substance mainly eliminated by the kidneys, in ad…
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A team of European scientists announces the creation of an electronic, wireless and implantable device under the skin that could be used to treat diabetes and obesity without medication. As explained by the researchers responsible for this work in an article published this Thursday in the journal 'Science', the first tests in mice performed with these implants have shown that their use allows to restore normal blood glucose values, favor weight …
The "diabesity", as obesity and type 2 diabetes is known to have become a global epidemic, could be on the verge of adding an ally that, for once, does not come from GLP-1 drugs but from electronics.A team of researchers from the Federal Polytechnic School of Zurich (ETH) has managed to develop a small implantable device that eliminates excess glucose in the blood by electric current, without resorting to the administration of drugs or insulin.T…
An implantable electronic device could become a non-pharmacological alternative to address obesity and type 2 diabetes, that is, diabetes.
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