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Chargers-Bills NFL Picks: Justin Herbert & Co. in Desperation Mode Sunday

Dimers gives Buffalo a 65% win chance and projects a 26-22 final after 10,000 simulations.

Summary by CBS Sports
The 0-2 Chargers face what seems like a must-win game Sunday in Buffalo

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CBS SportsCBS Sports
Center

Chargers-Bills NFL picks: Justin Herbert & Co. in desperation mode Sunday

The 0-2 Chargers face what seems like a must-win game Sunday in Buffalo

·Fort Lauderdale, United States
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Bills QB Josh Allen Faces Big Prediction Against Struggling Chargers

Buffalo Bills quarterback Josh Allen is expected to have another strong performance against the Los Angeles Chargers.

·Las Vegas, United States
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USA TodayUSA Today
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Bills' explosive offense gets reeling Chargers next

The red-hot 2-0 Bills host the disappointing 0-2 Chargers in Week 3 at Highmark Stadium. Here's an early look ahead to the matchup.

·New York, United States
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Syracuse NYSyracuse NY
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Early Bills vs. Chargers betting preview: Odds, picks, and predictions for NFL Week 3

Highmark Stadium sets the stage for the NFL matchup between the Los Angeles Chargers and Buffalo Bills on Sunday, September 27, 2026.

·New York, United States
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Syracuse NY broke the news in New York, United States on Sunday, September 20, 2026.
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