During aging, people with Down syndrome may face a higher risk of cardiovascular disease
- The study evaluated cardiovascular disease risk with aging in a cohort of 5,155 individuals with Down syndrome from Sweden, born between 1946 and 2000, by comparing them to matched controls from the general population.
- The study arose as longer life expectancy in Down syndrome reveals different age-related health risks and a distinct cardiovascular risk factor profile from the general population.
- Researchers determined that individuals with Down syndrome have more than four times the likelihood of experiencing an ischemic stroke and over five times the likelihood of a hemorrhagic stroke compared to others. While the overall incidence of heart attacks is comparable to the general population, younger people with Down syndrome face a heightened risk.
- Annie Pedersen, the lead author, noted that these findings may influence how healthcare providers monitor and manage cardiovascular health in people with Down syndrome as they age, reflecting changes in their risk for certain heart-related conditions.
- The findings suggest caregivers should monitor stroke risk closely and promote healthy lifestyle habits, as stroke risk factors may include congenital heart disease, diabetes, obesity, and high cholesterol.
27 Articles
27 Articles

Down Syndrome Patients Have Higher Stroke, Heart Attack Risk
Key Takeaways
During aging, people with Down syndrome may face a higher risk of cardiovascular disease
Because life expectancy for individuals with Down syndrome has increased dramatically, investigators assessed the risk of age-related cardiovascular diseases in this population. As reported in the Journal of Internal Medicine, the researchers found increased risks of various cardiovascular diseases compared with the general population.
The Down Syndrome Act – Update from member representatives – Learning Disability England
The Down Syndrome Act became law in 2022 – you can more about the act and watch some films made by the Down Syndrome Association here. Since 2021, Learning Disability England has been working with members on the Down Syndrome Act. Most Learning Disability England members said they did not want a separate Act. You […]
Down Syndrome Linked to Increased Risk of Stroke
Results from a Swedish study researching cardiovascular risk show that people with Down syndrome are at significantly increased risk of both ischemic and hemorrhagic stroke compared to those without the condition. Risks of other cardiovascular events, such as heart attack, were no higher in people with the genetic condition than in the rest of the population, although in people under the age of 40 years, people with Down syndrome had a higher ri…


Rewrite During aging, do people with Down syndrome face a higher risk of
Because life expectancy for individuals with Down syndrome has increased dramatically, investigators assessed the risk of age-related cardiovascular diseases in this population. As reported in the Journal of Internal Medicine, the researchers found increased risks of various cardiovascular diseases compared with the general population. In the study, 5,155 individuals with Down syndrome born in Sweden in 1946–2000 were compared with other Swedis…
Coverage Details
Bias Distribution
- 47% of the sources are Center
To view factuality data please Upgrade to Premium
Ownership
To view ownership data please Upgrade to Vantage