Duke researchers capture the first real-time 3D footage of viruses on the move, right before they hijack a cell
Capturing the start point of the virus–cell interaction with high-speed 3D single-virus tracking - Nature Methods
The early stages of the virus–cell interaction have long evaded observation by existing microscopy methods due to the rapid diffusion of virions in the extracellular space and the large three-dimensional cellular structures involved. Here we present an active-feedback single-particle tracking method with simultaneous volumetric imaging of the live cell environment called 3D-TrIm to address this knowledge gap. 3D-TrIm captures the extracellular p…
Scientists Record a Virus 'Prowling' Cells in Search of a Way Inside
For the first time, scientists have been able to make a three-dimensional, real-time recording of the moment a virus hijacks a cell, giving us a deeper level of understanding of how infections take hold in the body.