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Doublecortin Restricts Neuronal Branching by Regulating Tubulin Polyglutamylation

Summary by Stemwell Science News

Researchers used CRISPR/Cas9 to knock-out the Doublecortin gene in iPSCs and differentiated the cells into cortical neurons. DCX-KO neurons showed reduced velocities of nuclear movements and an increased number of neurites early in neuronal development. [Nature Communications] Full Article

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Stemwell Science News

Doublecortin Restricts Neuronal Branching by Regulating Tubulin Polyglutamylation

Researchers used CRISPR/Cas9 to knock-out the Doublecortin gene in iPSCs and differentiated the cells into cortical neurons. DCX-KO neurons showed reduced velocities of nuclear movements and an increased number of neurites early in neuronal development. [Nature Communications] Full Article

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Stemwell Science News broke the news in 1 day ago on Friday, February 21, 2025.

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