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Distinct Leukemogenic Mechanism of Acute Promyelocytic Leukemia Based on Genomic Structure of PML::RARα

Summary by Stemwell Science News

Investigators showed that leukemic stem cells of the short-type isoform acute promyelocytic leukemia (APL), a subtype of APL defined by different breakpoints of the PML gene, concentrated in the CD34+CD38− fraction and expressed T cell immunoglobulin mucin-3 (TIM-3). [Leukemia] Full Article

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Stemwell Science News

Distinct Leukemogenic Mechanism of Acute Promyelocytic Leukemia Based on Genomic Structure of PML::RARα

Investigators showed that leukemic stem cells of the short-type isoform acute promyelocytic leukemia (APL), a subtype of APL defined by different breakpoints of the PML gene, concentrated in the CD34+CD38− fraction and expressed T cell immunoglobulin mucin-3 (TIM-3). [Leukemia] Full Article

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Stemwell Science News broke the news in 1 day ago on Friday, February 21, 2025.

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