Discovery of low power cellular housekeeping in human oocytes could boost IVF success

A window into how the fallopian tube transports embryos

In vivo 3D OCT image, which shows the mouse oviduct with preimplantation embryos (red spheres) inside. Credit: Huan Han and Shang Wang, Stevens Institute of Technology The fallopian tube, also known as the oviduct, is responsible for several critical processes that lead to pregnancy. The tubular structure transports sperm and eggs, hosts fertilisation and shepherds preimplantation embryos toward the uterus as they develop. Shang Wang, an assista…

Discovery of low power cellular housekeeping in human oocytes could boost IVF success

Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published in The EMBO Journal shows that the cells deliberately slow the activity of their internal waste disposal systems as they mature, most likely an evolutionary design which keeps metabolism low and damage at bay.

How Human Eggs Stay Viable for Decades

Egg cells do not dispose of waste like other cells. Sebastian Kauritzki / Aramie Human eggs appear to manage waste differently than other cell types. All women are born with a limited supply of egg cells, or oocytes, expected to last around 50 years. This duration is remarkably extended for a single cell. Certain human [...] The post How Human Eggs Stay Viable for Decades appeared first on Mondo News.

Centre for Genomic Regulation Website

EN CASTELLANO/EN CATALÀ Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published today in The EMBO Journal shows that the cells deliberately slow the activity of their internal waste disposal systems as they mature, most likely an evolutionary design which keeps metabolism low and damage at bay. “By looking at more than a hundred freshly donated eggs, the largest dataset of its kind, w…