Innovative technology offers non-invasive way to observe blood clotting
- On May 15, 2025, scientists from a leading Tokyo institution introduced an innovative, non-invasive approach to monitor blood clotting in real-time among individuals with coronary artery disease.
- This method arose from challenges in monitoring platelet activity and the effectiveness of antiplatelet drugs, which affect clot formation and vary between individuals.
- The system combines a frequency-division multiplexed microscope and artificial intelligence to capture and analyze real-time platelet clumping using over 200 patient blood samples.
- Dr. Hirose stated that venous blood samples from the arm provide nearly the same platelet activity information as invasive coronary artery sampling, making the process safer and easier.
- The technology enables tailored antiplatelet therapy by revealing individual platelet behavior, opening paths to improved, personalized treatment and better cardiovascular risk management.
21 Articles
21 Articles
Detailed Vascular Anatomy of the Human Retina by Projection-Resolved Optical Coherence Tomography Angiography
Optical coherence tomography angiography (OCTA) is a noninvasive method of 3D imaging of the retinal and choroidal circulations. However, vascular depth discrimination is limited by superficial vessels projecting flow signal artifact onto deeper layers. The projection-resolved (PR) OCTA algorithm improves depth resolution by removing projection artifact while retaining in-situ flow signal from real blood vessels in deeper layers. This novel tech…
Seeing blood clots before they strike: Imaging technique shows how platelets behave in real time
Researchers from the University of Tokyo have found a way to observe clotting activity in blood as it happens—without needing invasive procedures. Using a new type of microscope and artificial intelligence (AI), their study shows how platelet clumping can be tracked in patients with coronary artery disease (CAD), opening the door to safer, more personalized treatment.
Detecting Blood Clots Before They Form: A Scientific Breakthrough
Researchers at the University of Tokyo have pioneered a groundbreaking technique that allows real-time observation of platelet clumping in blood, offering critical insights into clot formation in patients with coronary artery disease (CAD). By harnessing the power of a state-of-the-art frequency-division multiplexed (FDM) microscope combined with advanced artificial intelligence (AI) analysis, their study introduces a non-invasive method poised …
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