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CVS Opening First Pharmacy-only Location in Chicago

CVS aims to improve local pharmacy access with 20 new pharmacy-only stores nationwide, including five in Chicago, focusing on communities with limited options, CVS said.

  • On Monday, CVS Health unveiled its first pharmacy-only location at 2628 W. Pershing Road in Chicago's Brighton Park neighborhood, marking the first of nearly 20 such stores planned nationwide this year.
  • CVS is shifting toward 3,000-square-foot, pharmacy-only sites to improve access in underserved geographies, addressing reimbursement pressures and competition from online pharmacies that have challenged the retail pharmacy industry.
  • The Brighton Park location features all bilingual Spanish staff to serve a neighborhood where 85% of residents speak Spanish, and prioritizes face-to-face pharmacist interactions that 80% of CVS customers prefer.
  • 12th Ward Alderman Julia Ramirez praised the store's focus on health equity and language access, while U.S. Rep. Jesus "Chuy" Garcia welcomed not being "barraged with potato chips and pop" at the pharmacy-focused location.
  • CVS plans four additional pharmacy-only sites in Chicago and others in Houston and Detroit this year, expanding amid store closures by competitor Walgreens, which announced plans in 2024 to close 1,200 locations.
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CVS Pharmacy® celebrates opening of first pharmacy-only location in Chicago

Small, dedicated neighborhood pharmacies to open in select communities to help increase access to convenient pharmacy care

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NBC Chicago broke the news in Chicago, United States on Monday, March 30, 2026.
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