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COVID-19 vaccines may help some cancer patients fight tumors: Study

  • On October 19, 2025, investigators at The University of Texas MD Anderson Cancer Center reported that patients who received mRNA COVID vaccines within 100 days of starting immunotherapy were twice as likely to be alive after three years.
  • Researchers at The University of Texas MD Anderson Cancer Center traced the effect to mRNA vaccines acting as an immune alarm, supported by Grippin and Sayour's lab finding non-specific mRNA vaccines train immune systems to attack cancer.
  • In a study of over 1,000 patients treated from 2019 to 2023, 180 lung cancer patients had median survival of 37 months versus 20 months in 704 unvaccinated patients, and 43 vaccinated melanoma patients had not yet reached median survival compared to 167 unvaccinated.
  • Investigators found the biggest benefits in immunologically "cold" tumors, with survival gains most pronounced and immune activation plus higher PD-L1 suggesting sensitization to checkpoint inhibitors.
  • Despite the promise, researchers and independent experts warn the research is early and retrospective, requiring validation in randomized clinical trials amid recent US cuts to mRNA vaccine development funding.
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Corona vaccines could unexpectedly help cancer patients: mRNA vaccines seem to activate the immune system in such a way that immunotherapy works better.

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Medical Xpress broke the news in on Sunday, October 19, 2025.
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