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RNA Therapy May Help Preserve Muscle During GLP-1 Weight Loss

The combination cut lean-mass loss to about 5.5%, compared with about 10% for semaglutide alone, while improving glucose tolerance in mice.

Summary by Medical Xpress
GLP-1 drugs have revolutionized obesity treatment, but they can lead people to lose muscle mass along with fat. And when patients stop treatment, they often regain their weight—primarily as fat.

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Lean Right

Some people suffer setbacks after using weight loss medication, losing muscle along with fat. Rapid muscle loss makes one more susceptible to illness and slows down recovery. Scientists have opened a path to prevent muscle loss by using a method that promotes fat burning simultaneously with the use of weight loss drugs. A research team led by Professor Joseph Bass of Northwestern University School of Medicine stated, “RNA therapy [is similar to]…

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Medical Xpress broke the news in Douglas, United Kingdom on Monday, September 21, 2026.
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