US EditionA Startling Omega-3 Deficiency May Explain Women’s Alzheimer’s Risk
The study involving 841 participants found women with Alzheimer's have fewer healthy omega-3 fats and more unhealthy saturated fats, highlighting a sex-specific biological difference in the disease.
- On August 20, 2025, researchers from King’s College London and Queen Mary University London reported that women with Alzheimer’s disease have fewer omega fatty acid-carrying unsaturated fats than healthy women, while men show no such difference.
- Prompted by higher female diagnosis rates, researchers analyzed plasma from 841 participants in the AddNeuroMed cohort and the Dementia Case Register using mass spectrometry to profile 700 lipids.
- Researchers identified 32 lipids significantly associated with Alzheimer's in women, observing a steep rise in saturated lipids linked to worse cognitive test scores in affected women.
- Dr Cristina Legido-Quigley recommended women ensure omega fatty acids intake via fatty fish or supplements, while authors urged clinical trials to confirm effects on Alzheimer's progression.
- The findings position lipid biology as a sex-specific clue, highlighting a statistical indication of a causal link and the need for future diverse population studies given about 4.2 million women aged 65 and older affected.
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It has numerous properties with health benefits, such as being anti-inflammatory.How it should be consumed.
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Anti-Aging, Acupuncture and Health NewsWhat Was Unusual About Women With Alzheimer's?
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Could boosting omega-3 intake help lower Alzheimer's risk in women?
Women with Alzheimer's disease had fewer healthy fats and more unhealthy fats in their brains, a new study has found, suggesting that a higher intake of omega-3s may help lower the risk for this condition.
Dagens Nyheter.
hbl.fiWomen with Alzheimer's disease have unusually low levels of unsaturated fatty acids in their blood, a new study shows. Nothing similar is seen in men. "The difference between the sexes was the most shocking and unexpected finding," Cristina Legido-Quigley, one of the researchers behind the study, told The Guardian.
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