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Combination Therapy Shows 65% Response Rate in Rare Lymphoma

Summary by Inside Precision Medicine
A combination immunotherapy targeting PD-1 and CD38 achieved a 65% objective response rate in patients with relapsed extranodal NK/T-cell lymphoma (ENKTL), according to a multinational Phase II clinical trial by researchers from the National Cancer Centre Singapore (NCCS). The findings, published in Blood, also confirmed that specific genetic markers—including structural variations disrupting the 3′-UTR of the PD-L1 gene—can predict which patien…
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Inside Precision Medicine broke the news in on Wednesday, April 16, 2025.
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