Chargers’ Makeshift Offensive Line Faces Bigger Challenge Against Colts
Chargers aim to keep their AFC West lead as Khalil Mack returns from injury against Colts, who lead the AFC South and seek revenge for their only loss this season.
- On October 16, 2025, the Los Angeles Chargers host the Indianapolis Colts at SoFi Stadium on Sunday, with the Chargers leading the AFC West and the Colts topping the AFC South.
- Harbaugh, who quarterbacked the Colts in the 1990s, said his finest season was 1995, describing it as `dipped in magic waters` when playing for Indianapolis.
- Khalil Mack said he wants to play after sitting out four games, adding he's `slightly ready to go` since his activation window opened Tuesday, but GM Joe Hortiz and coach Jim Harbaugh will decide.
- Chargers defensive needs center on Mack's return against a high-powered Colts offense, and the game could affect playoff seeding in January.
- Injury updates show multiple Chargers limited or sidelined while Quentin Johnston, Chargers wide receiver, is cleared to play after missing last week. Joe Alt, Chargers left tackle, is listed as doubtful for Sunday after practicing Thursday and Friday.
15 Articles
15 Articles

Chargers’ makeshift offensive line faces bigger challenge against Colts
EL SEGUNDO — The injury report on Friday was mixed for the Chargers, who have suffered plenty of bumps, bruises, sprains and strains since training camp opened back in July and yet managed to record a 4-2 record going into Sunday’s game against the Indianapolis Colts at SoFi Stadium. Bad news first, as far as the Chargers were concerned. Right tackle Trey Pipkins III was ruled out for Sunday’s game because of a knee injury, sitting out for a sec…

Chargers’ Jim Harbaugh shares fond memories of quarterbacking ’95 Colts
EL SEGUNDO — Memories of Indy … “That was like being dipped in magic waters,” Chargers coach Jim Harbaugh said of playing with the Indianapolis Colts in the 1995 season, when he quarterbacked them to a 9-7 regular-season record and then guided them to the AFC championship game. “That’s what it felt like the entire season. “Everything just fell into place and you knew it. There was a great rapport among the players and coaches. It was a ball team…
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