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Closed-Loop Electrical Stimulation Prevents Focal Epilepsy Progression and Long-Term Memory Impairment

Summary by Nature
Interictal epileptiform discharges (IEDs) are expressed in epileptic networks and disrupt cognitive functions. It is unclear whether addressing IED-induced dysfunction could improve epilepsy outcomes, as most therapeutic approaches target seizures. We show, in a kindling model of progressive focal epilepsy, that IEDs produce pathological oscillatory coupling associated with prolonged, hypersynchronous neural spiking in synaptically connected cor…

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SUBMITTED Epilepsy is one of the most common neurological disorders with at least fifty million people worldwide. It is still underexposed what can happen if someone with epilepsy cannot cope well in daily life and at school. Epilepsy disrupts lives. It is important that people are aware of what treatment options are common in Suriname and where you can go for other questions. On Thursday evening there was a presentation organized by the Epileps…

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Scienmag: Latest Science and Health News broke the news in on Monday, June 23, 2025.
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