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Christian McCaffrey's Big Night Leads 49ers to 20-9 Victory over Panthers

Christian McCaffrey faces former team Carolina Panthers in a key NFC playoff game where winner gains crucial head-to-head tiebreaker, 49ers hold 7-4 record.

  • On Nov 24, 2025, the San Francisco 49ers hosted the Carolina Panthers at Levi's Stadium in a prime-time Week 12 game with NFC playoff stakes and a tiebreaker on the line.
  • Voiding a $25 million bonus in Brandon Aiyuk's deal reshaped the 49ers' practice availability this week as Christian McCaffrey faced the Panthers for the first time since the 2022 trade, while the team elevated Matt Gay with Eddy Piñeiro sidelined by a hamstring injury.
  • Christian McCaffrey totaled 142 scrimmage yards with a touchdown on 31 touches, marking his 10th 100-yard game, while Brock Purdy threw three first-half interceptions and finished 23-of-32 for 193 yards with one touchdown.
  • Monday night's 20-9 result improved the 49ers' record to 8-4 as San Francisco defeated Carolina, boosting their playoff odds from 86% to 91.3% according to ESPN's Football Power Index.
  • On Sunday the 49ers head to Cleveland with a chance for 9 wins while Carolina hosts the Rams next week, facing injuries including concussions to Jaycee Horn.
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Fox NewsFox News
+2 Reposted by 2 other sources
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Christian McCaffrey shines vs former Panthers, leads 49ers to Monday night victory

The San Francisco 49ers moved to 8-4 with a convincing 20-9 win over Carolina, keeping playoff hopes alive while the Panthers fell to 6-6.

·New York, United States
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Christian McCaffrey's big night leads 49ers to 20-9 victory over Panthers

Christian McCaffrey had a big night in his first game against Carolina since the Panthers traded him to San Francisco three years ago.

·United States
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Vanguardia broke the news in on Sunday, November 23, 2025.
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