Gut Probiotic Christensenella Tenuis Reduces Endotoxemia and Improves Metabolism in Obese Mice

Gut probiotic Christensenella tenuis reduces endotoxemia and improves metabolism in obese mice

This study is reported by the team of Professor Shuang-jiang Liu from Shandong University. The study reveals that the gut probiotic Christensenella tenuis significantly alleviates endotoxemia and metabolic disorders in a diet-induced obesity (DIO) mouse model by modulating gut bile acids (BAs) metabolism and suppressing lipopolysaccharide (LPS) translocation across the gut barrier.

Christensenella tenuis Suppresses Gut-Derived Endotoxins to Combat

A groundbreaking study led by Professor Shuang-jiang Liu and his team at Shandong University has unveiled novel insights into the interplay between gut microbiota, bile acids, and endotoxemia in metabolic disorders. Their research meticulously elucidates how the gut probiotic Christensenella tenuis exerts profound therapeutic effects by modulating bile acid metabolism and inhibiting systemic lipopolysaccharide (LPS) […]