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Cellular models of embryos offer insights into early developmental processes

Summary by News Medical
The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery.

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Cellular models of embryos offer insights into early developmental processes

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery.

·United States
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Science DailyScience Daily
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Scientists use cellular programming to mimic first days of embryonic development

Using CRISPR-based engineering methods to prompt stem cells to organize into embryo-like structures, scientists were able to create 'programmable' cellular models of embryos without ever experimenting with any actual embryos.

·United States
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Cells That Build Themselves Into an Embryo? Scientists Just Made It Happen

Scientists have found a way to study early embryonic development without real embryos. Using CRISPR, they programmed stem cells to self-organize into structures mimicking early embryos. The cells show remarkable, collective behavior, almost as if they instinctively “know” what to do. This breakthrough allows researchers to explore genetic influences on development, reproductive challenges, and potential [...]

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GEN - Genetic Engineering and Biotechnology News…GEN - Genetic Engineering and Biotechnology News…

Epigenetic Editing of Mouse Stem Cells Generates Embryoids for Developmental Research

Scientists at the University of California, Santa Cruz (UCSC), used CRISPR to engineer cellular models of embryos that mimic what happens in the first few days after reproductive cells meet. These embryoids are self-organized, three-dimensional cultures that mimic aspects of early embryonic development. Scientists can use these models to study how specific genes influence early development as well as to better understand developmental disorders …

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Sci Tech Daily broke the news in on Thursday, March 20, 2025.
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