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CDK6 Kinase Inhibition Unmasks Metabolic Dependencies in BCR::ABL1+ Leukemia

Summary by Stemwell Science News
Investigators explored the role of CDK6 in the regulation of cellular metabolism in BCR::ABL1+ leukemic cells. Cells lacking kinase active CDK6 displayed altered mitochondria morphology with a defective electron transport chain. [Cell Death & Disease] Full Article
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CDK6 Kinase Inhibition Unmasks Metabolic Dependencies in BCR::ABL1+ Leukemia

Investigators explored the role of CDK6 in the regulation of cellular metabolism in BCR::ABL1+ leukemic cells. Cells lacking kinase active CDK6 displayed altered mitochondria morphology with a defective electron transport chain. [Cell Death & Disease] Full Article

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Stemwell Science News broke the news in on Friday, February 21, 2025.
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