US EditionNew Research Uncovers Link Between Cancer Pathway and Blood-Retina Barrier Function
HENNEPIN COUNTY, MINNESOTA, JUL 10 – The tumor-suppressing protein p53 disrupts key signaling in brain and retina blood vessels, with NCAPH identified as a gene linked to inherited retinal and vascular diseases.
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New research uncovers link between cancer pathway and blood-retina barrier function
A University of Minnesota Medical School-led research team has discovered that a cancer signaling pathway has previously unrecognized roles in retina and brain blood vessels. The findings were recently published in Science Signaling.
Cancer Pathway Found to Weaken Brain and Eye Barriers
Researchers have uncovered a surprising connection between a cancer-related signaling pathway and the blood-brain and blood-retina barriers. The study shows that the tumor-suppressing protein p53 weakens the Norrin/Frizzled4 pathway, which is crucial for maintaining these protective barriers.
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