Call to ‘stand up’ on prostate cancer funding

Call to ‘stand up’ on prostate cancer funding

The widow of a stalwart WA farmer who took his life amid a battle with prostate cancer is calling on politicians to ‘stand up’ and pay more attention to the disease killing Australian men.

JCI Serotonin sets up neutrophil extracellular traps to promote neuroendocrine prostate cancer metastasis in the liver

Castration-resistant prostate cancer frequently metastasizes to the liver, and prostate cancer liver metastases often present a neuroendocrine phenotype (i.e., neuroendocrine prostate cancer [NEPC]), but the underlying molecular underpinnings remain unclear. In this issue of the JCI, Liu et al. demonstrate that the neurotransmitter serotonin (also known as 5-hydroxytryptamine), produced by NEPC cells, gained access to and activated neutrophils b…

Evaluation of maintenance of the common androgen deprivation therapy with the new antiandrogen therapy in patients with castration-resistant prostate cancer: a systematic review

Advanced prostate cancer does not respond to traditional androgen deprivation therapy (ADT) at some point in the treatment. The development of new hormonal