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C. diff uses toxic compound to fuel growth advantage

Summary by Science Daily
The pathogen C. diff -- the most common cause of health care-associated infectious diarrhea -- can use a compound that kills the human gut's resident microbes to survive and grow, giving it a competitive advantage in the infected gut. A team has discovered how C. diff (Clostridioides difficile) converts the poisonous compound 4-thiouracil, which could come from foods like broccoli, into a usable nutrient. Their findings increase understanding of…

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C. diff uses toxic compound to fuel growth advantage

The pathogen C. diff -- the most common cause of health care-associated infectious diarrhea -- can use a compound that kills the human gut's resident microbes to survive and grow, giving it a competitive advantage in the infected gut. A team has discovered how C. diff (Clostridioides difficile) converts the poisonous compound 4-thiouracil, which could come from foods like broccoli, into a usable nutrient. Their findings increase understanding of…

·United States
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GEN - Genetic Engineering and Biotechnology News…GEN - Genetic Engineering and Biotechnology News…

Toxic Compound Gives C. difficile Competitive Advantage in Infected Gut

The pathogen Clostridioides difficile (C. difficile) is the most common cause of healthcare-associated infectious diarrhea. A team led by investigators at Vanderbilt University Medical Center has now found that C. difficile can use a compound that kills the human gut’s resident microbes to survive and grow, giving it a competitive advantage in the infected gut. The team, headed by Eric Skaar, PhD, the Ernest W. Goodpasture Professor of Pathology…

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ecotopical.comecotopical.com

C. diff uses toxic compound to fuel growth advantage, researchers discover

The pathogen C. diff-the most common cause of health care-associated infectious diarrhea-can use a compound that kills the human gut's resident microbes to survive and grow, giving it a competitive advantage in the infected gut.

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ecotopical.com broke the news in on Tuesday, March 25, 2025.
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