US EditionCell death discovery could lead to next-gen drugs for neurodegenerative conditions
- On May 12, 2025, scientists at Melbourne's WEHI discovered a compound that prevents cell death by targeting the protein BAX.
- This discovery followed screening over 100,000 compounds to find one that prevents BAX from damaging mitochondria, the cell's energy producers.
- A recent investigation led by WEHI aims to create therapies capable of altering the course of neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
- Professor Grant Dewson expressed great enthusiasm about discovering a new small compound that can inhibit the activity of the damaging protein BAX.
- This breakthrough may lead to therapies capable of reducing or halting neuron loss, addressing the current absence of options to slow Parkinson’s disease progression.
13 Articles
13 Articles
Cell death discovery could lead to next-gen drugs for neurodegenerative conditions
Researchers have discovered how to block cells dying, in a finding that could lead to new treatments for neurodegenerative conditions like Parkinson's and Alzheimer's. The team has identified a small molecule that can selectively block cell death.
Scientists Find Molecule That Blocks Brain Cell Death In Parkinson's, Alzheimer's
A team of Australian scientists has identified a small molecule that blocks cell death, an advance that could lead to new treatments for neurodegenerative conditions like Parkinson's and Alzheimer's.
Fixing cellular recycling centers may help treat neurodegenerative diseases
For neurodegenerative diseases such as Alzheimer's and Parkinson's, treatment options are scant. New research by Stanford scientists illuminates a promising target for treatment—increasing a lipid that boosts the trash-sorting functions of cells.
Scientists Discover Molecule That Halts Brain Cell Death in Parkinson's and Alzheimer's - teleSUR English
The breakthrough centers on a compound that inhibits BAX, the ‘cell killer’ protein. On Monday, an Australian medical institute confirmed that scientists have identified a small molecule that blocks cell death, offering hope for treatments that could slow or stop the progression of neurodegenerative diseases like Parkinson’s and Alzheimer’s. RELATED: Birds Offer Clues to Fighting Human Respiratory Diseases “Currently, there are no treatments tha…
Cell Death Blocking Protein Discovery Could Lead to Next-Gen Parkinson's Treatments
A team of scientists in Australia has discovered a small molecule that selectively blocks a key protein involved in cell death, a finding that could lead to the development of treatments for neurodegenerative conditions such as Parkinson’s disease and Alzheimer’s disease (AD). The study, led by researchers at the Walter and Eliza Hall Institute of Medical Research (WEHI) and published in Science Advances, identifies a compound named WEHI-3773 th…
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