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ASCENT-03 Trial Supports Standard Use of Sacituzumab Govitecan in mTNBC

Although the ORR was similar among patients treated with sacituzumab govitecan vs chemotherapy for TNBC, the DOR was higher with the sacituzumab govitecan.
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Drug-antibody conjugated drugs (ADCs), known as "Trojan Horses", are more effective than conventional chemotherapy to treat metastatic breast cancer. For the first time, they have become the new standard of first-line treatment in metastatic triple negative breast cancer rather than chemotherapy, so far first-choice treatment, as concluded by the international clinical trial ASCENT-03.

A clinical trial has reinforced as a therapeutic option drug-antibody conjugated drugs (ADCs), which act as a Trojan horse and are more effective than conventional chemotherapy to treat metastatic breast cancer.These are the conclusions of the international clinical trial ASCENT-03, led by the IBCC-Pangaea Oncology, at the Oncology Institute Chirónsalud Teknon in Barcelona, and the IOB Madrid, and published on Sunday The New England Journal of M…

A clinical trial has reinforced as a therapeutic option drug-antibody conjugated drugs (ADCs), which act as a Trojan horse and are more effective than conventional chemotherapy to treat metastatic breast cancer. These are the conclusions of the international clinical trial ASCENT-03, led by the IBCC-Pangaea Oncology, at the Oncology Institute Chirónsalud Teknon in Barcelona, and the IOB Madrid, and published on Sunday The New England Journal of …

·Madrid, Spain
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diarioestrategia.cl broke the news in on Sunday, October 19, 2025.
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