Bat-specific adaptations in interferon signaling and GBP1 contribute to enhanced antiviral capacity
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Bat-specific adaptations in interferon signaling and GBP1 contribute to enhanced antiviral capacity
Bat-specific adaptations in interferon signaling and GBP1 contribute to enhanced antiviral capacity Bats are reservoirs of emerging zoonotic viruses that may cause severe disease in humans and agricultural animals. However, it is poorly understood how bats can tolerate diverse viral infections. Here, we characterized type I interferon response pathways in kidney cell lines derived from two divergent bat species, Pteropus alecto and Eptesicus fus…
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