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Atomic swap in morphine core structure leads to safer, non-rewarding opioid alternative

Summary by Phys.org
One of the greatest revolutions in the field of pain medication was the isolation of morphine from the opium poppy in the 19th century. Morphine molecules act as painkillers by attaching themselves to the µ-opioid receptor (MOR) in the central nervous system and blocking the brain from sending pain signals to the rest of the body. This potent opioid analgesic also has side effects such as constipation, respiratory depression, and even serious ad…

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Phys.org broke the news in United Kingdom on Tuesday, July 15, 2025.
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