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Innovent Presents Updated IBI363 Data in Colorectal Cancer at ASCO 2025

  • Innovent Biologics announced on June 1, 2025, updated Phase 1 and 2 clinical data of IBI363 for colorectal cancer and melanoma at ASCO 2025 in San Francisco and Suzhou, China.
  • The data follow prior immunotherapy treatments and focus on unresectable mucosal and acral melanoma, addressing cold tumors resistant to conventional therapies.
  • Among 31 patients treated at 1 mg/kg biweekly, IBI363 showed a 23.3% confirmed objective response rate and a 76.7% disease control rate, with median progression-free survival of 5.7 months.
  • The median overall survival reached 14.8 months with 61.5% 12-month survival, and treatment-related adverse events like arthralgia and rash were mostly Grade 1 or 2 and manageable.
  • These results support ongoing pivotal trials comparing IBI363 to pembrolizumab in untreated mucosal and acral melanoma, suggesting potential for broader clinical use and improved patient outcomes.
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ASCO 2025 Oral Presentation: Innovent Biologics Announces Updated Data of IBI363 (First-in-class PD-1/IL-2α -bias Bispecific Antibody Fusion Protein) from Phase 1 and 2 Clinical Studies on Immunotherapy-treated Advanced Malignant Melanoma

SAN FRANCISCO and SUZHOU, China, June 1, 2025 /PRNewswire/ -- Innovent Biologics, Inc (Suzhou) (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and commercializes high-quality medicines for the treatment of oncology, cardiovascular and metabolic, autoimmune, ophthalmology and other major…

·Helena, United States
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The Billings Gazette broke the news in Billings, United States on Sunday, June 1, 2025.
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