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AP Biosciences charts course for safer CD137 bispecifics with T-cube

Summary by Drug Discovery and Development
AP Biosciences is building the protocol around one key objective: confirm that conditional CD137 agonism, a tumor-restricted T-cell costimulation, can be delivered safely in patients whose HER2-positive solid tumors express the p95HER2 variant, a truncated, drug-resistant form of HER2. To that end, it recently dosed the first patient in the Phase 1/2 trial of its… The post AP Biosciences charts course for safer CD137 bispecifics with its T-cube …
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Drug Discovery and Development broke the news in on Monday, April 28, 2025.
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