Iris Melanocytic Tumours in New Zealand/Aotearoa: Presentation, Management and Outcome in a High UV Exposure Environment

Iris melanocytic tumours in New Zealand/Aotearoa: presentation, management and outcome in a high UV exposure environment

Iris melanoma, a rare intraocular malignancy, represents the smallest subgroup of uveal melanoma. This first, comprehensive study of iris melanocytic lesions in the high ultraviolet environment in New Zealand/ Aotearoa (NZ) examines diagnosis, management and outcomes. Retrospective study of iris melanocytic tumours referred to tertiary referral centres in Auckland, NZ, over 20 years (1999-2018). Data analysed include demographics, tumour charact…

Antibiotics and energy inhibitors effectively kill aggressive melanoma cells by blocking mitochondrial pathways

Researchers have discovered that the most aggressive melanomas, the deadliest form of skin cancer, overactivate two key processes in mitochondria, the components of cells that provide energy. Blocking these pathways with currently available drugs effectively killed melanoma cells.

New Study Uncovers Key Mechanisms Driving Skin Cancer Aggressiveness and

A groundbreaking discovery in melanoma research has unveiled a crucial biological vulnerability in this notoriously aggressive form of skin cancer. Scientists have identified that the most lethal melanomas excessively activate two essential mitochondrial processes, which ultimately fuel the cancer cells’ relentless growth and survival. These revelations offer a promising new avenue for targeted therapies, leveraging available drugs to selectivel…