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Ancient DNA finally solves the mystery of the world’s first pandemic

Summary by Science Daily
Scientists have finally uncovered direct genetic evidence of Yersinia pestis — the bacterium behind the Plague of Justinian — in a mass grave in Jerash, Jordan. This long-sought discovery resolves a centuries-old debate, confirming that the plague that devastated the Byzantine Empire truly was caused by the same pathogen behind later outbreaks like the Black Death.

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The Justinian plague, which appeared in 541 C.E., caused millions of deaths and contributed to the lasting weakening of the Byzantine Empire. Yet, until recently, no direct genetic evidence had been found in the areas at the heart of this pandemic, leaving doubt about the pathogen actually involved. An interdisciplinary team from the University of South Florida (USF) and Florida Atlantic University (FAU), in collaboration with Indian and Austral…

Scientists have deciphered the genome of the bacterium responsible for the world's first recorded pandemic, which swept the eastern Mediterranean about 1,500 years ago. Researchers have identified the… The culprit of the first pandemic in humanity has been discovered - ΙΝΑΦΤΕΜΟΠΟΡΙΚΙ

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observatorial.com broke the news in on Friday, August 29, 2025.
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