Experimental drug looks to be gastric bypass surgery in pill form

Experimental drug looks to be gastric bypass surgery in pill form

Daily drug creates temporary coating in small intestine.

An Experimental Obesity Pill Mimics Gastric Bypass Surgery

A novel drug that produces a temporary coating in the small intestine could be a new strategy for weight loss—and an alternative to surgeries and GLP-1 drugs.

SYNT-101 once-daily oral treatment for obesity mimics RYGB

Syntis Bio has announced positive preclinical and first-in-human data for its lead candidate, SYNT-101, an investigational once-daily oral treatment for obesity. The data were presented at the European Congress on Obesity and Weight Management (Obesity 2025) in Barcelona.SYNT-101 is being developed as a once-daily pill for the treatment of obesity. It works by transiently blocking nutrient absorption in the duodenum, the upper part of the small …