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She Was the World’s Oldest Person, Living to 117. What Do Her Genes Reveal About the Secret of Longevity?

  • Maria Branyas Morera, verified as the world's oldest person, died aged 117 on 19 August 2024 in Spain after participating in a longevity study.
  • Researchers studied her genetics, microbiome, and lifestyle to understand her extreme lifespan, noting this is a single case with potential survivorship bias.
  • Her biological age was about 23 years younger than chronological age, linked to low inflammation, excellent cardiovascular health, and a gut microbiome enriched in Bifidobacterium.
  • The study highlighted her efficient lipid metabolism, exceptional genome with protective variants, no alcohol or smoking, and a Mediterranean diet including daily plain, sugar-free yogurt.
  • Scientists use these findings to explore healthy aging biomarkers and strategies for longevity, emphasizing that old age does not inherently mean poor health.
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Longevity Secrets From The World's Oldest Person

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Nature broke the news in United Kingdom on Wednesday, September 24, 2025.
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