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Age-related neuroinflammation and exacerbated immune responses in PINK1 and PARK2 knockout mice with experimental autoimmune encephalomyelitis

Summary by researchsquare.com
Recent studies suggest that the E3 ubiquitin ligase PARKIN and PTEN-induced kinase 1 (PINK1) contribute to age-related immune regulation and neuroinflammation, though the precise mechanisms remain unclear. In this study, we induced active experimental autoimmune encephalomyelitis (EAE) in midd...
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Age-related neuroinflammation and exacerbated immune responses in PINK1 and PARK2 knockout mice with experimental autoimmune encephalomyelitis

Recent studies suggest that the E3 ubiquitin ligase PARKIN and PTEN-induced kinase 1 (PINK1) contribute to age-related immune regulation and neuroinflammation, though the precise mechanisms remain unclear. In this study, we induced active experimental autoimmune encephalomyelitis (EAE) in midd...

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researchsquare.com broke the news in on Wednesday, March 26, 2025.
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