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After Quitting Antidepressants, some People Suffer Surprising, Lingering Symptoms

UNITED STATES, JUL 9 – Advocates and researchers emphasize the need for better tapering guidelines and recognition of prolonged antidepressant withdrawal, with some patients suffering symptoms for an average of eight years.

  • In response to patient reports, the American Psychiatric Association began investigating long-term withdrawal symptoms, marking a significant shift driven by advocacy efforts.
  • Patient advocacy groups and online communities, led by Adele Framer since 2011, have mobilized to push for research and recognition of prolonged antidepressant withdrawal symptoms, amid lack of large-scale studies.
  • German meta-analysis found one in six antidepressant users report withdrawal symptoms, with long-term sufferers averaging eight years; NHS survey shows long-term users are 18 times more likely to experience lasting effects.
  • In response to patient advocacy, the Canadian government began funding PSSD research at UBC, while the Psychotropic Deprescribing Council develops tapering guidelines.
  • Experts warn that millions face long-lasting withdrawal symptoms, revealing a widespread public health issue that is still poorly understood and under-researched.
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Few mental health practices are more debated than the long-term use of antidepressant drugs, which are prescribed to approximately one in nine adults in the United States, according to data from the Centers for Disease Control and Prevention. The reassessment began in 2019, when two British researchers published a study that found that 56 percent of patients suffered withdrawal symptoms when they stopped taking antidepressant drugs and 46 percen…

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npr broke the news in Washington, United States on Wednesday, July 9, 2025.
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