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New Treatment Cuts Bad Cholesterol by Nearly 50% without Statins

Summary by Science Daily
A new breakthrough could change how high cholesterol is treated, offering a powerful alternative to traditional drugs. Researchers have developed tiny DNA-based molecules that shut down PCSK9—a key protein that keeps “bad” LDL cholesterol circulating in the blood. By blocking this protein, cells can absorb more cholesterol instead of letting it build up in arteries, dramatically lowering levels linked to heart disease.

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The IndependentThe Independent
+2 Reposted by 2 other sources
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Scientists develop single jab to cut ‘bad’ cholesterol levels by half

Patients show 52 per cent drop in bad cholesterol levels within six months

·London, United Kingdom
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According to new research, a small-scale gene editing study conducted in China found that a single dose of an experimental injection halved "bad" cholesterol levels within six months of treatment. This treatment is being developed for familial hypercholesterolemia, a life-threatening inherited disease that leads to abnormally high levels of fat in the blood. Patients suffering from this condition live with a 10 to 20 times higher risk of heart a…

A single-dose treatment based on CRISPR technology reduced LDL cholesterol levels to one year by up to 52.5% in patients with resistance to conventional treatments in a clinical trial. The treatment seeks to reproduce the effects of natural variants of loss of function of d的ANGPTL3 by causing a change [...] This article A single dose of CRISPR causes the "bad" cholesterol to drop by 52.5% in a clinical trial appeared first on Trust My Science.

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Trust My Science broke the news on Tuesday, September 8, 2026.
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