US EditionA Brain Circuit for Apathy: New Research Maps How Inflammation Dials Down Motivation in Advanced Cancer
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A Brain Circuit for Apathy: New Research Maps How Inflammation Dials Down Motivation in Advanced Cancer
In a new study that redefines how scientists understand the brain’s response to chronic illness, including cancer, researchers have identified a dedicated neural circuit that senses inflammation in the body and directly suppresses motivation via the brain’s dopamine system. Published in Cell, the findings offer an explanation for a symptom that has long puzzled clinicians: the profound apathy and fatigue seen in people with inflammatory diseases…
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