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2.2% A1C Reduction: Lilly's Mounjaro Achieves Breakthrough in First-Ever Youth Type 2 Diabetes Trial

Summary by stocktitan.net
Phase 3 SURPASS-PEDS trial shows Mounjaro reduced A1C by 2.2% and BMI by 11.2% in children with type 2 diabetes. 86.1% achieved target A1C of ≤6.5% at 30 weeks.

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Lilly's Mounjaro (tirzepatide), a GIP/GLP-1 dual receptor agonist, reduced A1C by an average of 2.2% in a Phase 3 trial of children and adolescents with type 2 diabetes

In SURPASS-PEDS, Mounjaro met the primary and all key secondary endpoints at 30 weeks and showed sustained improvement in glycemic control and continued BMI reduction through the study's 52-week extension

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The study included 10 to 17-year-olds with type 2 diabetes, and was presented at the European Diabetes Association conference in Vienna. • Following the results, a change in age registration is expected.

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PR Newswire broke the news in United States on Wednesday, September 17, 2025.
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