DB-OTO Results in the New England Journal of Medicine Showcase Dramatic and Sustained ...

DB-OTO Results in the New England Journal of Medicine Showcase Dramatic and Sustained ...

Nearly all participants (11 of 12) experienced clinically meaningful hearing improvements, including three who achieved normal hearing; eight with longer follow-up showed stability or continued improvement in their hearing

DB-OTO Results in theNew England Journal of Medicine Showcase Dramatic and Sustained Improvements in Hearing and Speech Perception in Children with Profound Genetic Hearing Loss

Nearly all participants (11 of 12) experienced clinically meaningful hearing improvements, including three who achieved normal hearing; eight with longer follow-up showed stability or continued improvement in their hearing Among three who completed speech assessments, all showed significant improvement with one able to identify one- and two-syllable words with no visual cues and respond to […] The post DB-OTO Results in theNew England Journal of…

11 of 12 kids improved — Regeneron DB-OTO shows hearing gains; NEJM data, U.S. filing planned

Regeneron's DB-OTO (CHORD trial) produced clinically meaningful hearing gains in 11 of 12 participants; 9 met the ≤70 dBHL primary endpoint at week 24, 8 had ≥36-week follow-up and no DB-OTO-related adverse findings.