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In total, 39 have been published by Sickle Cell Disease News which Ground News has aggregated in the past 3 months.

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Top Sickle Cell Disease News News

Gene-editing therapy OTQ923 cuts stroke risk in 3 SCD patients

Mississippi · Mississippi

Gene-editing therapy OTQ923 cuts stroke risk in 3 SCD patients

The investigational gene-editing therapy OTQ923 resulted in normalization of the speed of blood flow in the brain of three adults with sickle cell disease (SCD), according to data from a Phase 1 clinical trial. Findings suggest the treatment could help lower the risk of stroke in patients. The study (NCT04443907), sponsored by Novartis Pharmaceuticals, was stopped early due to commercial reasons, as the company discontinued its SCD gene-editing …Read Article

Dosing started in Phase 1 study of novel SCD therapy CLY-124

Volunteering · Maryland

Dosing started in Phase 1 study of novel SCD therapy CLY-124

The first healthy volunteer has been dosed in a Phase 1 study of Cellarity's novel globin-switching therapy CLY-124 for sickle cell disease.Read Article

What I’ve learned about life, love, and sacrifice due to caregiving

United States · United States

What I’ve learned about life, love, and sacrifice due to caregiving

Being a caregiver to someone with sickle cell disease isn’t a role anyone can truly prepare for. It’s a calling that finds us, and it stems from love, loyalty, and necessity. My caregiving journey began with caring for my cousin, a vibrant, witty, and spirited soul whose strength never ceases to amaze me. Along this journey, I’ve learned more than I ever thought possible and feel inclined to share it with you. Caregiving will test the extent of …Read Article

ED pain scores may predict future hospitalization for SCD children

Higher pain scores at the time of discharge from the emergency department (ED) may predict the likelihood of hospitalization in children with sickle cell disease (SCD) who seek emergency care for acute pain episodes, according to a study in the U.S. The study also found that patients with severe pain upon both ED arrival and discharge, and who received multiple opioid doses for pain management but were not prescribed opioids upon discharge, were…Mississippi · Mississippi Read Article

Buprenorphine may reduce opioid use for sickle cell disease adults

Adults with sickle cell disease (SCD) who are started on buprenorphine to ease chronic pain — either in a clinical setting or at home via telemedicine — may be able to reduce their use of opioids and visit the hospital less frequently, a small study suggests. Buprenorphine induction — the process of carefully starting buprenorphine treatment during early opioid withdrawal to control symptoms and avoid side effects — typically follows a tradition…Opioids · New York Read Article

First Subject Dosed In Cellarity’s Trial Of CLY-124 For SCD - Data Intelligence

Sickle cell disease leads to pain crises, chronic inflammation, and organ damage. Credit: Yuriy K/Shutterstock. Cellarity has dosed the first subject in a Phase I study of oral medication, CLY-124, to treat sickle cell disease (SCD). This development follows the US Food and Drug Administration’s (FDA) clearance of the company’s investigational new drug application. The global trial will evaluate the tolerability, pharmacokinetic, and safety prof…See the Story

NANA Talk: Leroy Jones & Albert Campbell Discuss Sickle Cell Awareness and Community Advocacy

________________________________________________________________________ On this episode of NANA Talk, Leroy Jones, Executive Director of Neighbors And Neighbors Association, Inc., welcomes special guest Albert Campbell, Founder of Shakevia's Sickle Cell Anemia Foundation, for a powerful conversation on advocacy, resilience, and community-driven change. For more shows, go to: www.communitynewspapers.com/cnewstv ABOUT US: Miami Community Newspape…Miami, Florida · Miami See the Story

BEAM-101 shows sustained benefits as treatment for sickle cell

BEAM-101, a one-time, gene-edited cell therapy, continues to show durable therapeutic benefits more than one year after treatment in people with sickle cell disease (SCD), according to new data from the Phase 1/2 BEACON trial. The treatment’s developer, Beam Therapeutics, shared data from the first 17 patients dosed in the trial in a presentation, “Base editing for sickle cell disease: ongoing results from the BEACON study evaluating the safety …Maryland · Maryland Read Article

Man Battles Sickle Cell From Hospital and Advocates for Awareness

67% Right coverage: 3 sources

Source: BojanMirkovic / Getty INDIANAPOLIS – For Kyle Law, the sterile white walls of a hospital room are a familiar sight. The 28-year-old Educator from Pike Township is currently in the hospital, in the midst of another “pain crisis” brought on by a disease he’s been fighting since he was just six months old. His mother, Nicole Law, knows this battle intimately. She was diagnosed at age three. As Indiana prepares to recognize World Sickle Cell…Juneteenth See the Story

This World Sickle Cell Day, I’m grateful for UK advocacy groups

In honor of World Sickle Cell Day, held June 19, I would like to highlight some incredible U.K.-based organizations I’ve had the pleasure of working with recently. These groups are not only changing the narrative of what it means to live with sickle cell disease, but they’re also challenging stigmas and expanding perceptions about what those of us with the condition can achieve. One standout organization is Black Blood Matters UK, which leads im…United Kingdom · United Kingdom Read Article

Why Genotype Compatibility Matters In Sickle Cell Prevention - NEWS AGENCY OF NIGERIA

Why Genotype Compatibility matters in Sickle Cell prevention 14 total views todayBy Uche Bibilari, News Agency of Nigeria (NAN) Sickle Cell Disease (SCD) is a genetic blood disorder that arises when both parents carry the sickle cell gene, creating a 25 per cent chance of transmitting the disease to their offspring with each pregnancy. Globally, an estimated 400,000 babies are born annually with […] NEWS AGENCY OF NIGERIA See the Story

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