
News about Ludwigshafen
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CRISPR · LudwigshafenMitochondrial genome mutations are associated with various diseases and gene therapy targeted to mitochondria has the potential to effectively treat such diseases. Here, we targeted a point mutation in mitochondrial DNA (mtDNA) that can cause mitochondrial diseases via delivery of the clustered, regularly interspaced, short palindromic repeats/Cas9 (CRISPR/Cas9) system to mitochondria using an innovative lipid nanoparticle (LNP) delivery system.…See the Story
Lipid Nanoparticle Delivery of the CRISPR/Cas9 System Directly Into the Mitochondria of Cells Carrying m.7778G>T Mutation in MtDNA (Mt-Atp8)
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