When Bats Whisper MERS: The Silent Mutations Pushing a New Coronavirus Toward Humans
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When Bats Whisper MERS: The Silent Mutations Pushing a New Coronavirus Toward Humans
The headline sounds apocalyptic, yet the data behind it are mounting. In April 2025, a Cell paper unveiled a new lineage of HKU5-CoV that efficiently binds human ACE2 and infects cultured airway epithelia—a molecular feat previously unseen among MERS-related bat viruses (Cell, 2025). Weeks later, a Nature study on a mink coronavirus (MRCoV) confirmed the same ACE2 lock-picking trick in a separate merbecovirus branch (Nature, 2025). Add a Februar…
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