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Weight loss jabs: are they really worth it as new study finds users regain weight faster than dieters
Oxford researchers found weight regain after stopping GLP-1 drugs is about 0.3 kg per month faster than after ending diet or exercise programs.
- On January 11, 2026, researchers from Oxford's Nuffield Department of Primary Care Health Sciences found people stopping weight-loss drugs regain weight faster than after ending behavioural programmes by 0.3 kg monthly.
- A surge in GLP-1 receptor agonists such as semaglutide and tirzepatide has led around 1.5 million people in the UK to use these drugs, with many stopping within 12 months.
- Researchers pooled 37 studies and tracked more than 9,000 adults with average treatment 39 weeks and follow-up 32 weeks, finding weight regain of around 0.4 kilograms a month and projected return to original weight in 18 months.
- NICE recommended post-treatment support for GLP-1 users over one year, while Dr Sam West urged health systems to use these medicines effectively and sustainably.
- GLP-1s produce large weight losses but benefits can reverse, with heart-health measures returning after 1.4 years, raising cost-effectiveness concerns for national health systems, Garron Dodd said.
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People who refuse to take drugs for the weak return to their initial lose weight in less than two years, much faster than those who follow any other weakness plan, according to a study cited by The Guardian.
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Coverage Details
Total News Sources11
Leaning Left1Leaning Right0Center6Last UpdatedBias Distribution86% Center
Bias Distribution
- 86% of the sources are Center
86% Center
14%
C 86%
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