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Prostate cancer treatment with potential for fewer side effects to be trialled in UK

The trial will recruit 280 patients globally to assess if Aquablation reduces side effects like erectile dysfunction compared to radical prostatectomy, improving quality of life, researchers said.

  • In the UK, a NIHR-backed trial has launched to test Aquablation against radical prostatectomy, with the Royal Marsden in London first to recruit and Procept BioRobotics sponsoring across three countries.
  • Because radical prostatectomy can cause serious side-effects such as infection and erectile dysfunction, researchers and consultant urological surgeons are testing Aquablation to minimise these risks and preserve continence and sexual activity.
  • Using a robotic high-pressure waterjet, Aquablation lets surgeons employ real-time ultrasound mapping and AI guidance to remove cancerous tissue while sparing nerves and muscles, and is used for benign prostatic hyperplasia .
  • The trial will recruit 280 patients worldwide with early-stage, localised prostate cancer, enrolling at more than 25 centres including Royal Marsden, Guy's and St Thomas' NHS Foundation Trust, Royal Free London NHS Foundation Trust, and Norfolk and Norwich University Hospitals NHS Foundation Trust.
  • Following the UKNSC draft, Health Secretary Wes Streeting said earlier this week he was surprised that experts expect data within two years from a Prostate Cancer UK trial combining PSA test and rapid MRI, and Aquablation could add a global alternative surgical option.
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14 Articles

Sky News UKSky News UK
+2 Reposted by 2 other sources
Center

Prostate cancer treatment with potential for fewer side effects to be trialled in UK

The therapy - which involves a robotic-assisted, high-pressure water jet - is less invasive than traditional surgery.

·United Kingdom
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Evening StandardEvening Standard
+6 Reposted by 6 other sources
Center

Trial for prostate cancer treatment with fewer side-effects launches in UK

The treatment is suitable for men whose cancer has not spread outside of the prostate gland or has spread to the area just outside the gland.

·London, United Kingdom
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The Independent broke the news in London, United Kingdom on Saturday, December 6, 2025.
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