Michigan State Visits No. 25 USC in Big Ten Matchup

Michigan State visits No. 25 USC in Big Ten matchup

The No. 25 USC Trojans and the Michigan State Spartans play in a matchup of Big Ten foes.

USC vs Michigan State Prediction Football Picks Today 9/20/25

The Michigan State Spartans and USC Trojans meet Saturday in college football action at Los Angeles Memorial Coliseum. Here’s a USC vs Michigan State Prediction. This article will include a USC vs Michigan State Pick. Michigan State Spartans Betting Preview The Michigan State Spartans beat Boston College and Youngstown State and plays Nebraska next. The Michigan State Spartans have won 4 of their last 5 games. Aidan Chiles is completing 71.6 per…